
Summary
- Tamayo & Yushiro: Demon allies aiding demon slayers through scientific research.
- Tanjiro & Hotaru: Comical relationship between a swordsman and his dedicated swordsmith.
- Shinobu & Kanao: Hashira mentor and her reserved apprentice develop a deep bond.
Demon Slayer, the transformative shonen anime, has begun the final stages of its engrossing story, following the path of swordsman Tanjiro Kamado and the Demon Slayers as they try to rid the world of demons and their fearsome leader, Muzan Kibutsuji. With the release of Demon Slayer: Kimetsu no Yaiba – The Movie: Infinity Castle right around the corner, the climax of the story is not far away, with the revolutionary anime delivering shockwaves within the industry in recent years.
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In Demon Slayer, numerous memorable duos have emerged during Tanjiro’s journey, excelling as tandems in combat, sharing camaraderie, or demonstrating a great understanding of one another, bringing a special element to the visually stimulating anime.
8
Tamayo & Yushiro
Demon Allies That Aid Tanjiro And Nezuko
While many in the Demon Slayer Corp have a deep hatred for demons and their murderous intent, there are a select few demons that opt not to devour humans, with Tamayo and her assistant Yushiro being two examples of demons that aid demon slayers, such as Tanjiro and his sister Nezuko, through the powers of scientific research. After freeing herself from an aggressive demonic state after being turned by Muzan, Tamayo dedicates herself to finding a cure for demons, with her loyal assistant, Yushiro, a former terminally ill child who was turned into a demon to save his life, aiding Tamayo in her efforts.
While Yushiro’s jealousy comes out when Tanjiro spends time with Tamayo, Yushiro fights for the same dream as Tamayo, with the demon tandem working in the shadows, seeking to turn the tide of the demon war.
7
Tanjiro Komado & Hotaru Haganezuka
Comical Relationship Between A Swordsman And His Swordsmith
One of the funniest and most turbulent relationships in all of Demon Slayer belongs to the tandem of Tanjiro and his swordsmith, Hotaru Haganezuka, a man who often becomes enraged whenever Tanjiro needs a new sword to wield. Utterly devoted to his cherished creations, Hotaru cares for little else but his swords, with Tanjiro’s treatment of his prized works of art providing plenty of humor to the anime.
The duo’s starring moments occur during the Swordsmith Village Arc, where Hotaru’s dedication to restoring a sword for Tanjiro’s use, along with his actions while being at risk of great peril, show Tanjiro a glimpse of his swordsmith’s commitment to aiding him on his path as a demon slayer, deepening their connection.
6
Shinobu Kocho & Kanao Tsuyuri
Hashira Mentor And Her Reserved Apprentice
One of the few Hashiras to have been a mentor to a fellow demon slayer is Shinobu Kocho, who looks after and mentors Kanao Tsuyuri, a timid and scarred girl who becomes part of her family at the behest of her sister Kanae. Coming into Shinobu’s service after experiencing a traumatic upbringing marred by neglect and abuse, Kanao becomes the adoptive sister of the Kocho siblings, with Shinobu in particular resembling a role model for Kanao as she follows in her footsteps in becoming a demon slayer.

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Despite their standing in the Demon Slayer Corps, Shinobu and her sister both come to teach and nurture Kanao, developing her into a talented demon slayer with sky-high potential.
5
Obanai Iguro & Sanemi Shinazugawa
Hashira Hardheads That Form A Formidable Tandem
Out of the esteemed Hashira, the two most hardened and cruel of the bunch happen to be the Serpent and Wind Hashira’s, Obanai Iguro and Sanemi Shinazugawa. Known for their unforgiving and brash natures, the pair form a friendly and competitive relationship that often sees Iguro and Shinazugawa sparring, drawing the best out of each other. The pair usually share core beliefs, with their mutual hatred of Tanjiro intensifying since his arrival in the Demon Slayer Corps.
In the riveting Hashira Training Arc opener, the dynamic duo’s slaughter of demons in pursuit of Muzan’s plans offers a glimpse into the tandem’s chemistry and no-nonsense attitude toward killing demons, with the pair being a force to be reckoned with when operating in sync.
4
Daki & Gyutaro
Demonic Duo Emerge As Great Threats To Tanjiro And Friends
Demon Slayer‘s peak of the Entertainment District Arc introduced the villainous siblings, Daki and Gyutaro, the Upper Rank Six demons that pushed Tanjiro, Zenitsu, Inosuke, and Hashira Tengen Uzui to their utter limits. Growing up poor and disadvantaged, Gyutaro always sought to protect his little sister Daki, with their eventual turning into demons seeing the pair become significant threats to demon slayers alike, with the only way of defeating the pair being to behead both simultaneously.
Besides their unparalleled synergy, the siblings relied on each other intensely, with Daki valuing her brother’s protection above all else. At the same time, Gyutaro always strove to safeguard his sister at all costs, even pushing Daki away in the afterlife, with their end seeing Gyutaro and Daki staying together.
3
Tanjiro & Zenitsu
New Gen Demon Slayers That Push Each Other To Greatness
During Tanjiro’s adventures, he encounters Zenitsu, a dramatic demon slayer who frequently experiences mood swings, with the pair developing their prowess side by side as they embark on their hardened and challenging journeys. First meeting in the Final Selection Arc, Tanjiro and Zenitsu’s relationship often revolves around Tanjiro reassuring Zenitsu, as the blond-haired swordsman’s anxious tendencies hinder his ability to perform when first called upon.

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Besides Zenitsu’s thirst for women, including Tanjiro’s demon sister Nezuko, the pair display an exceptional understanding throughout their battles, often aiding each other when it matters most, a true friendship built on camaraderie and trust.
2
Zenitsu & Inosuke
Tanjiro’s Best Friends That Excel Particularly During The Entertainment District Arc
While Tanjiro is a talented and special demon slayer, the hearty protagonist has help along the way, with his two closest friends, Inosuke and Zenitsu, forming an amusing but strong friendship that grows throughout Demon Slayer. Starting as frenemies, the pair, who hold completely contrasting personas, with Inosuke’s wild and blunt behavior, and Zenitsu’s sensitive and outlandish reactions, concoct a duo full of fun and bizarreness.
Both Zenitsu and Inosuke have their moment to shine in the Entertainment District Arc under the leadership of Tengen, where they embrace their comical potential together when they go undercover in the search for upper-rank demons. What unfolds is the development of their relationship, as their chemistry and creativity in combat against Daki showcase their unrivaled bond, which continues to grow from strength to strength all the way up to Infinity Castle.
1
Tanjiro & Nezuko Kamado
Brother And Sister Who Stay Side By Side Despite Nezuko Becoming A Demon
Demon Slayer‘s most important tandem is the siblings of Tanjiro and Nezuko Kamado, a beloved brother who cares for his dear sister after an attack on their home leaves most of their family dead, except for Nezuko. However, the protagonist’s sister is transformed into a demon, causing a strain in their relationship as they learn to cope with Nezuko’s condition and Tanjiro’s rise within the Demon Slayer Corps.
Despite Nezuko’s transition into becoming a demon, Tanjiro vows to protect his little sister no matter the cost, fighting side by side with Nezuko, as well as defending her from the likes of some of the big shots within the Hashira, who initially despise her existence. As Tanjiro continues to fight a frightening number of formidable demons, Nezuko is always along for the ride, with their bond ever-growing over the years as Nezuko soon withstands the sun, priming the pair for their eventual showdown with Muzan.